Homedog grooming

Frontline vs Advantix: Which Is Better?

Like Tweet Pin it Share Share Email

Ticks, fleas often nest on pets, bringing concerns to the pet lovers. Not only do they harm the pets, but they also have the potential to cause illness and contaminate our home. Consequently, dog worm treatment has always been a solution to resolve this dilemma. And again, we rely on medicine to do that!

For flea-and-tick killing products, Frontline and Advantix are probably the two most outstanding brands on the market recently because of their effectiveness and safety. But you don’t need to go with both brands, right! So, Frontline vs Advantix – which one is the better choice for the health of your pet. Our post today can help you!

The Ingredients


A Frontline product can be used on dogs and cats from 8 weeks or more, and weighing from 5 to 22 pounds. Its main function is to prevent and treat fleas, ticks, egg, lice, etc. For a bigger size of dogs (from 23 to 44 pounds), you can go with this product that has the same function as the first product.

Most Frontline products contain two active ingredients:

  • Fipronil: It is able to kill fleas and ticks if they eat or touch it. In the same way, insects can be eliminated by crawling through your dog’s fur.
  • Methoprene: It acts like a typical regulator to the development of them. This medicine limits the productive extent of flea (eggs, pupae, and larvae) from maturing into adult fleas.
  • According to the manufacturer, the formula helps to prevent and cut the harassment of ticks and fleas, making them die within 12 hours. In addition, the drug controls reinfection for a long time. It is waterproof and convenient to use, too.


    It’s not recommended to use Advantix products on any animals apart from dogs, especially, not for the ones under the weight of 4 lbs. Advantix prevents and treats bugs, fleas, mosquitoes, lice, and biting flies on only dogs.
    The manufacturer (the Bayer Group) says that the drop keeps away and slays ticks, consisting of Deer ticks (carriers of Lyme disease and anaplasmosis), American dog ticks (carriers of spotted fever, tularemia and ehrlichiosis), Brown dog ones (carriers of ehrlichiosis, anaplasmosis, bartonellosis, hemoplasmosis, babesiosis and Rocky Mountain spotted fever), and Lone Star ticks (carriers of ehrlichiosis and tularemia).
    According to Bayer, Advantix is special due to the supplement of Imidacloprid to its active ingredients, including pyriproxyfen and permethrin. Imidacloprid can be found naturally in plants like tobacco or nicotine that are deadly to insects. It has the capability of controlling sucking insects on owners. However, Advantix II contains toxic permethrin for cats, and this is the ingredient that you should avoid.
    The drop brings a variety of benefits in eliminating and killing all life periods of ticks, preventing all vectors on treated pooches from overrunning into your home, getting rid of fleas in around 12 hours and preventing plagues within a month. It is also waterproof and easy to use.

    The Bottom Lines

  • Both products get rid of 98-100% existing fleas and ticks on dogs within 12 hours of using.
  • They eliminate the whole flea life’s cycle.
  • They keep working for 30 days.
  • Only Advantix possesses a perfect ingredient, helping repel and kill fleas and ticks, mosquitoes, and lice. Advantix also prevents biting flies before they act.
  • Frontline brings an ingredient which has an off-label use as fly and mosquito prevention.

The Usage


Take the tube out of the bag. Keep the tube upright and break the tip of the tube. Remember to let it away from children.

Place the tube on the skin between the shoulder blades. Squeeze the tube gently so that enough solution in the tube is spread on the skin of your cat or dog. It must be applied on the skin rather than on the fur, you it must be careful to avoid excessive stick to the fur. Just one tube for one treatment is sufficient.

For the more illustrative way to see how to apply Frontline to your dog, check a look at this video:


  • Keep out of reach of children.
  • Avoid contact with treated areas until dry.
  • No repeated treatment within 30 days.


After detaching applicator tube from the bag, peel down foil by using scissors. Take hold of applicator tube in a straight position and then pull the cap off the tube. Revolve around the cap and set another end of cap back on the tube.

Next, wrench cap in order to break the seal for the removal of the cap from tube. You should let your dog stand up to apply the drop easier. Steadily apply enough content of the tube to two or more points on the dog’s back from the shoulder to the tail.

At each spot, divide into the hair for the observation of skin. Set its tip on the skin and gently squeeze it to push a part of the solution onto the skin. Not applying too much this at any point to avoid making the solution run out the side of the dog. Use one tube per treatment for any dogs, from 10 lbs to 55 lbs (depending on each product).

For the more illustrative way to see how to apply Frontline to your dog, check a look at this video:


    Keep the drop away from your dog’s eyes, or prevent him from eating it.

    Dispose of the empty tube.

    In case of serious pest infestation, re-treatment can be carried out more than four weeks. Avoid re-treatment more than once every seven days. After the disease is controlled, return to the monthly treatment schedule.

    The Bottom Lines

      Frontline is suitable and ensured for dogs of all life’s circle and even pregnant/nursing dogs.

      Advantix is harmful to cats, while frontline can be used for cats.

      Two products show that humans need to have exercise caution in use

      Both of them can be applied to dogs as young as eight weeks old.

      Advantix requires a minimum weight.

The Efficiency


After being applied to your pet, the drop quickly spreads across the skin within 24 to 48 hours and concentrates on the oil glands in the skin.

Frontline can kill fleas for 24 hours and ticks for 48 hours. After a month, it can destroyed the flea's life cycles. Frontline can also kill mature eggs, larvae, and fleas for up to 6 weeks.

The product is waterproof and still works well after bathing with shampoo, swimming or drying in the sun.


It has imidacloprid and permethrin to end all life stages of fleas, ticks, and mosquitoes. Both substances work on contact, affecting their nerve cells at different positions. Together with Pyriproxyfen, an ingredient is an insect growth regulator.

It can kill fleas on dogs for up to 12 hours, along with the ability to prevent further flea carriers for 4 weeks. Based on the environmental conditions, pre-existing pupae can reappear for 6 weeks or longer.

The product is waterproof and still works well after bathing with shampoo, swimming or drying in the sun.

The Bottom Lines

    Both Advantix and Frontline work for one month.

    They allow your pet to bath or swim when the treatment dries.


Each product brings many benefits and some minor limits as well. The most important thing is that they work to treat dog parasites, like ticks and fleas, not mention to preventing dermatitis and killing eggs. With just a few simple steps, you can remove all sorts of parasites that are causing pain and discomfort to your pet.

Hopefully, this useful post helps you choose the right product for your pet. Thank you for reading!

Related post :

how to get rid of fleas on your dog ?

Why is My Dog Itching

Comments (0)

Post a Comment

%d bloggers like this: